Basic Information
ID: ALA930554
Type: Binding
Description: Inhibition of BACE1 in CHO cells expressing human APP assessed as reduction of amyloid beta production
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA930554
ED50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.08 | 5.45 | 5.45 |
| 497.04 | 4.71 | 4.71 |
| 496.01 | 3.96 | 3.96 |
| 468.99 | 4.08 | 4.08 |
| 484.98 | 3.05 | 3.05 |
| 482.97 | 4.17 | 4.17 |
| 481.98 | 3.57 | 3.57 |
| 497.00 | 4.56 | 4.56 |
| 509.05 | 5.00 | 5.00 |
| 537.06 | 5.34 | 5.34 |
| 376.50 | 3.42 | 3.42 |
| 481.64 | 4.84 | 4.84 |
| 486.69 | 5.36 | 5.36 |
| 486.69 | 5.36 | 5.36 |
| 472.59 | 3.95 | 3.95 |
| 487.67 | 5.02 | 5.02 |
| 458.65 | 5.39 | 5.39 |
| 474.65 | 4.36 | 4.36 |
| 450.58 | 2.41 | 2.41 |
| 484.65 | 4.34 | 4.34 |
| 434.58 | 3.43 | 3.43 |
| 434.58 | 3.43 | 3.43 |
| 448.61 | 3.83 | 3.83 |
| 420.56 | 3.05 | 3.05 |
| 429.57 | 3.97 | 3.97 |
| 434.58 | 3.44 | 3.44 |
| 547.06 | 5.61 | 5.61 |
| 443.60 | 4.36 | 4.36 |
| 490.99 | 5.49 | 5.49 |
| 555.00 | 6.31 | 6.31 |
| 507.06 | 5.96 | 5.96 |
| 511.02 | 4.46 | 4.46 |
| 519.05 | 4.98 | 4.98 |