Basic Information
ID: ALA932847
Type: Functional
Description: Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA932847
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.99 | 5.03 | 5.03 |
| 497.60 | 4.39 | 4.39 |
| 437.55 | 4.37 | 4.37 |
| 497.60 | 4.39 | 4.39 |
| 477.61 | 4.06 | 4.06 |
| 427.51 | 3.97 | 3.97 |
| 477.61 | 4.06 | 4.06 |
| 463.58 | 3.67 | 3.67 |
| 449.56 | 3.43 | 3.43 |
| 520.59 | 4.70 | 4.70 |
| 525.65 | 5.17 | 5.17 |
| 511.63 | 4.78 | 4.78 |
| 483.57 | 4.46 | 4.46 |
| 476.58 | 4.85 | 4.85 |
| 495.67 | 5.74 | 5.74 |
| 437.54 | 3.58 | 3.58 |
| 427.51 | 3.10 | 3.10 |
| 441.54 | 3.33 | 3.33 |
| 441.54 | 3.33 | 3.33 |
| 427.51 | 3.97 | 3.97 |
| 443.58 | 4.43 | 4.43 |
| 443.58 | 4.43 | 4.43 |
| 442.52 | 3.67 | 3.67 |
| 442.52 | 3.67 | 3.67 |
| 438.54 | 3.77 | 3.77 |
| 438.54 | 3.77 | 3.77 |
| 474.57 | 3.82 | 3.82 |
| 487.61 | 5.53 | 5.53 |