Basic Information
ID: ALA932852
Type: Functional
Description: Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP-induced calcium flux by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA932852
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.16 | 3.09 | 3.09 |
| 318.21 | 4.61 | 4.61 |
| 334.21 | 3.89 | 3.89 |
| 320.18 | 3.58 | 3.58 |
| 320.18 | 3.58 | 3.58 |
| 412.28 | 5.37 | 5.37 |
| 347.25 | 4.80 | 4.80 |
| 379.25 | 4.20 | 4.20 |
| 397.29 | 3.59 | 3.59 |
| 365.29 | 4.91 | 4.91 |
| 363.25 | 4.58 | 4.58 |
| 460.41 | 4.50 | 4.50 |
| 475.38 | 2.58 | 2.58 |
| 349.22 | 4.19 | 4.19 |
| 416.34 | 5.62 | 5.62 |
| 413.27 | 4.77 | 4.77 |
| 349.22 | 4.19 | 4.19 |
| 349.22 | 4.19 | 4.19 |
| 402.31 | 5.31 | 5.31 |
| 389.29 | 4.18 | 4.18 |
| 333.22 | 4.49 | 4.49 |
| 333.22 | 4.49 | 4.49 |
| 333.22 | 4.49 | 4.49 |
| 319.20 | 4.19 | 4.19 |
| 402.31 | 5.31 | 5.31 |
| 320.18 | 3.58 | 3.58 |
| 334.21 | 3.89 | 3.89 |
| 413.27 | 4.77 | 4.77 |
| 389.16 | 5.22 | 5.22 |
| 390.27 | 4.15 | 4.15 |
| 335.19 | 4.33 | 4.33 |
| 349.22 | 4.72 | 4.72 |
| 405.29 | 3.42 | 3.42 |
| 305.17 | 4.32 | 4.32 |
| 319.20 | 4.63 | 4.63 |
| 333.22 | 4.88 | 4.88 |
| 389.29 | 4.18 | 4.18 |
| 375.26 | 3.79 | 3.79 |