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Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assay

Basic Information

ID: ALA938929

Type: Binding

Description: Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assay

Format: BAO_0000219

Cell type: MCF7/Topo

Target:  ATP-binding cassette sub-family G member 2(ALA5393)

Document:  ALA1140935

Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA938929

IC50

Total(17)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
515.106.486.48
646.746.376.37
563.655.565.56
379.462.942.94
469.583.643.64
644.736.146.14
644.736.146.14
645.725.545.54
644.736.146.14
609.684.694.69
595.664.394.39
594.674.994.99
616.726.376.37
646.746.376.37
616.726.376.37
600.726.676.67
625.792.782.78
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