Inhibition of CRM1-mediated nucleocytoplasmic transport of RevM5 mutant in HEK293 cells assessed as RevM5-GFP nuclear localization at 2 ug/ml after 2 ...

Basic Information

ID: ALA940322

Type: Binding

Description: Inhibition of CRM1-mediated nucleocytoplasmic transport of RevM5 mutant in HEK293 cells assessed as RevM5-GFP nuclear localization at 2 ug/ml after 2 hrs by fluorescence microscopy

Format: BAO_0000219

Cell type: HEK293

Target: Exportin-1(ALA5661)

Document: ALA1152253

Inhibition of CRM1-mediated nucleocytoplasmic transport of RevM5 mutant in HEK293 cells assessed as RevM5-GFP nuclear localization at 2 ug/ml after 2 hrs by fluorescence microscopy: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA940322

Activity

Total(39)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
146.15	0.87	0.87
242.28	2.58	2.58
242.28	2.58	2.58
242.28	2.58	2.58
195.61	1.10	1.10
180.60	1.52	1.52
180.60	1.52	1.52
180.60	1.52	1.52
164.14	1.01	1.01
225.05	1.63	1.63
272.05	1.47	1.47
244.25	1.37	1.37
293.71	1.61	1.61
293.71	1.61	1.61
278.70	2.03	2.03
278.70	2.03	2.03
278.70	2.03	2.03
278.70	2.03	2.03
262.24	1.51	1.51
262.24	1.51	1.51
323.15	2.14	2.14
370.15	1.98	1.98
168.16	-0.29	-0.29
168.16	-0.29	-0.29
278.70	2.03	2.03
278.70	2.03	2.03
278.70	2.03	2.03
278.70	2.03	2.03
278.70	2.03	2.03
262.24	1.51	1.51
262.24	1.51	1.51
323.15	2.14	2.14
323.15	2.14	2.14
370.15	1.98	1.98
370.15	1.98	1.98
244.25	1.37	1.37
258.28	1.56	1.56
242.28	2.58	2.58
242.28	2.58	2.58