Basic Information
ID: ALA941165
Type: Binding
Description: Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21 (DE3) cells assessed as formation of 1,10-dioic acid metabolite by liquid scintillation
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BL21-DE3
Target: Squalene synthetase(ALA3338)
Document: ALA1140905
Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21 (DE3) cells assessed as formation of 1,10-dioic acid metabolite by liquid scintillation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA941165
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.66 | 3.38 | 3.38 |
| 500.63 | 3.19 | 3.19 |
| 540.74 | 4.41 | 4.41 |
| 542.71 | 4.15 | 4.15 |
| 590.76 | 4.78 | 4.78 |
| 500.63 | 3.19 | 3.19 |
| 500.63 | 3.19 | 3.19 |
| 522.64 | 3.36 | 3.36 |
| 482.58 | 4.08 | 4.08 |
| 590.63 | 4.38 | 4.38 |
| 518.62 | 3.33 | 3.33 |
| 568.63 | 4.21 | 4.21 |
| 484.63 | 3.07 | 3.07 |
| 520.61 | 3.35 | 3.35 |
| 542.71 | 3.86 | 3.86 |
| 472.58 | 2.41 | 2.41 |
| 486.61 | 2.80 | 2.80 |
| 499.65 | 3.14 | 3.14 |
| 498.66 | 2.99 | 2.99 |
| 500.63 | 3.19 | 3.19 |
| 525.69 | 3.53 | 3.53 |
| 518.62 | 3.33 | 3.33 |
| 518.62 | 3.33 | 3.33 |
| 568.63 | 4.21 | 4.21 |
| 568.63 | 4.21 | 4.21 |
| 535.08 | 3.85 | 3.85 |
| 556.74 | 4.49 | 4.49 |
| 590.76 | 4.78 | 4.78 |
| 516.63 | 2.90 | 2.90 |
| 592.73 | 4.99 | 4.99 |
| 566.69 | 4.45 | 4.45 |
| 536.61 | 3.47 | 3.47 |
| 569.52 | 4.50 | 4.50 |
| 540.65 | 3.94 | 3.94 |
| 536.61 | 3.47 | 3.47 |
| 569.52 | 4.50 | 4.50 |
| 536.61 | 3.47 | 3.47 |
| 548.65 | 3.34 | 3.34 |