Basic Information
ID: ALA944276
Type: Binding
Description: Inhibition of human recombinant EGFR
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA944276
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 510.52 | 5.79 | 5.79 |
| 506.63 | 4.36 | 4.36 |
| 581.07 | 6.14 | 6.14 |
| 520.66 | 4.70 | 4.70 |
| 383.45 | 5.52 | 5.52 |
| 343.39 | 4.66 | 4.66 |
| 357.41 | 4.96 | 4.96 |
| 616.66 | 5.55 | 5.55 |
| 520.66 | 4.75 | 4.75 |
| 369.22 | 4.26 | 4.26 |
| 398.22 | 3.57 | 3.57 |
| 453.39 | 4.61 | 4.61 |
| 414.26 | 2.84 | 2.84 |
| 396.29 | 4.68 | 4.68 |
| 456.34 | 3.40 | 3.40 |
| 440.30 | 4.13 | 4.13 |
| 454.33 | 4.22 | 4.22 |
| 340.18 | 4.01 | 4.01 |
| 411.31 | 4.05 | 4.05 |
| 354.21 | 4.02 | 4.02 |
| 369.22 | 4.26 | 4.26 |
| 316.16 | 3.11 | 3.11 |
| 344.22 | 3.60 | 3.60 |
| 330.19 | 3.57 | 3.57 |
| 446.91 | 4.28 | 4.28 |
| 295.34 | 3.70 | 3.70 |
| 381.23 | 4.10 | 4.10 |
| 424.30 | 3.64 | 3.64 |
| 360.22 | 2.94 | 2.94 |
| 387.29 | 3.50 | 3.50 |
| 494.35 | 0.40 | 0.40 |
| 404.27 | 2.32 | 2.32 |
| 404.27 | 2.32 | 2.32 |
| 424.31 | 4.23 | 4.23 |
| 374.24 | 2.96 | 2.96 |
| 461.36 | 2.62 | 2.62 |
| 447.34 | 2.23 | 2.23 |
| 391.52 | 3.13 | 3.13 |
| 456.39 | 3.58 | 3.58 |
| 459.35 | 3.68 | 3.68 |
| 443.35 | 3.67 | 3.67 |
| 429.32 | 3.28 | 3.28 |
| 374.20 | 3.03 | 3.03 |
| 345.41 | 3.45 | 3.45 |
| 265.32 | 3.12 | 3.12 |
| 378.48 | 3.21 | 3.21 |
| 350.47 | 3.83 | 3.83 |
| 424.28 | 2.83 | 2.83 |
| 402.25 | 3.81 | 3.81 |
| 359.44 | 3.78 | 3.78 |
| 401.31 | 3.53 | 3.53 |
| 429.37 | 4.67 | 4.67 |
| 415.34 | 4.28 | 4.28 |
| 388.23 | 3.05 | 3.05 |
| 388.23 | 3.42 | 3.42 |
| 401.31 | 3.89 | 3.89 |
| 480.32 | 0.38 | 0.38 |
| 390.24 | 2.30 | 2.30 |
| 390.24 | 2.30 | 2.30 |
| 410.28 | 3.91 | 3.91 |
| 331.18 | 2.82 | 2.82 |
| 457.38 | 4.06 | 4.06 |
| 375.25 | 3.78 | 3.78 |
| 391.25 | 3.45 | 3.45 |
| 513.96 | 2.89 | 2.89 |
| 405.28 | 4.02 | 4.02 |
| 406.27 | 3.42 | 3.42 |
| 401.86 | 5.25 | 5.25 |
| 391.44 | 4.49 | 4.49 |
| 419.85 | 5.39 | 5.39 |
| 185.19 | 0.86 | 0.86 |
| 313.72 | 3.81 | 3.81 |
| 383.21 | 3.68 | 3.68 |
| 372.31 | 3.94 | 3.94 |
| 322.30 | 3.06 | 3.06 |
| 372.31 | 3.94 | 3.94 |
| 329.32 | 2.79 | 2.79 |
| 349.31 | 2.83 | 2.83 |
| 485.95 | 3.63 | 3.63 |
| 499.97 | 3.66 | 3.66 |
| 498.00 | 5.03 | 5.03 |
| 369.22 | 3.83 | 3.83 |
| 562.67 | 4.70 | 4.70 |
| 383.25 | 4.39 | 4.39 |
| 383.25 | 4.22 | 4.22 |
| 382.26 | 4.82 | 4.82 |
| 383.25 | 4.22 | 4.22 |
| 382.26 | 4.82 | 4.82 |
| 403.67 | 4.40 | 4.40 |
| 436.23 | 5.37 | 5.37 |
| 395.26 | 4.38 | 4.38 |
| 380.25 | 4.59 | 4.59 |
| 445.32 | 5.36 | 5.36 |
| 410.27 | 4.39 | 4.39 |
| 368.23 | 4.11 | 4.11 |
| 425.33 | 4.17 | 4.17 |
| 455.36 | 4.05 | 4.05 |
| 598.13 | 6.00 | 6.00 |
| 412.24 | 3.89 | 3.89 |
| 440.30 | 4.37 | 4.37 |
| 441.29 | 3.76 | 3.76 |
| 440.35 | 4.32 | 4.32 |
| 496.41 | 4.48 | 4.48 |
| 495.42 | 5.09 | 5.09 |
| 497.39 | 4.30 | 4.30 |
| 496.41 | 3.87 | 3.87 |
| 497.40 | 3.27 | 3.27 |
| 438.55 | 3.15 | 3.15 |
| 525.45 | 4.05 | 4.05 |
| 539.43 | 3.04 | 3.04 |
| 520.39 | 3.60 | 3.60 |
| 511.42 | 3.83 | 3.83 |
| 466.97 | 3.96 | 3.96 |
| 554.69 | 4.00 | 4.00 |
| 573.09 | 5.54 | 5.54 |
| 410.25 | 2.22 | 2.22 |
| 401.85 | 3.83 | 3.83 |
| 493.30 | 3.78 | 3.78 |
| 502.31 | 5.85 | 5.85 |
| 509.83 | 3.98 | 3.98 |
| 383.25 | 4.65 | 4.65 |
| 724.42 | 8.11 | 8.11 |
| 325.76 | 3.55 | 3.55 |
| 312.76 | 2.89 | 2.89 |
| 427.31 | 3.44 | 3.44 |
| 429.88 | 3.48 | 3.48 |
| 457.94 | 4.28 | 4.28 |
| 417.87 | 3.48 | 3.48 |
| 417.87 | 3.48 | 3.48 |
| 492.00 | 4.42 | 4.42 |
| 292.34 | 2.55 | 2.55 |
| 346.31 | 3.26 | 3.26 |
| 370.41 | 4.03 | 4.03 |
| 384.44 | 3.82 | 3.82 |
| 293.33 | 2.02 | 2.02 |
| 445.93 | 4.26 | 4.26 |
| 545.69 | 5.21 | 5.21 |
| 569.72 | 5.03 | 5.03 |
| 613.69 | 6.23 | 6.23 |
| 580.14 | 5.86 | 5.86 |
| 376.19 | 2.61 | 2.61 |
| 331.74 | 2.50 | 2.50 |
| 358.20 | 3.59 | 3.59 |
| 376.19 | 3.73 | 3.73 |
| 444.34 | 5.79 | 5.79 |
| 484.35 | 4.66 | 4.66 |
| 511.42 | 4.97 | 4.97 |
| 523.48 | 5.61 | 5.61 |
| 511.42 | 4.21 | 4.21 |
| 483.41 | 4.83 | 4.83 |
| 492.38 | 4.77 | 4.77 |
| 481.35 | 3.73 | 3.73 |
| 327.19 | 4.06 | 4.06 |
| 497.39 | 4.58 | 4.58 |
| 470.93 | 4.61 | 4.61 |
| 442.92 | 5.22 | 5.22 |
| 484.96 | 4.99 | 4.99 |
| 513.51 | 5.93 | 5.93 |
| 303.37 | 3.65 | 3.65 |
| 458.61 | 5.15 | 5.15 |
| 446.55 | 3.75 | 3.75 |
| 386.22 | 4.25 | 4.25 |
| 341.21 | 4.09 | 4.09 |
| 401.26 | 2.81 | 2.81 |
| 398.31 | 4.02 | 4.02 |
| 412.34 | 4.41 | 4.41 |
| 468.36 | 3.70 | 3.70 |
| 383.85 | 5.85 | 5.85 |
| 529.41 | 4.35 | 4.35 |
| 341.77 | 4.14 | 4.14 |
| 484.96 | 4.24 | 4.24 |
| 473.93 | 4.31 | 4.31 |
| 482.38 | 4.09 | 4.09 |
| 385.22 | 3.54 | 3.54 |
| 466.34 | 4.02 | 4.02 |
| 342.76 | 3.53 | 3.53 |
| 481.96 | 4.27 | 4.27 |
| 483.98 | 4.19 | 4.19 |
| 372.79 | 3.54 | 3.54 |
| 416.84 | 3.56 | 3.56 |