Basic Information
ID: ALA944279
Type: Binding
Description: Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr before LPS challenge by whole cell assay
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA944279
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 177.25 | 1.23 | 1.23 |
| 229.12 | 1.77 | 1.77 |
| 243.15 | 2.33 | 2.33 |
| 257.18 | 2.72 | 2.72 |
| 367.90 | 2.56 | 2.56 |
| 349.28 | 2.46 | 2.46 |
| 294.19 | 1.19 | 1.19 |