Therapeutic index, ratio of plasma concentration causing emesis to IC50 for inhibition of LPS-stimulated TNFalpha release in squirrel monkey whole blo...

Basic Information

ID: ALA945962

Type: ADME

Description: Therapeutic index, ratio of plasma concentration causing emesis to IC50 for inhibition of LPS-stimulated TNFalpha release in squirrel monkey whole blood

Format: BAO_0000366

Organism: Saimiri sciureus

Tissue: Plasma

Target: ADMET(ALA612558)

Document: ALA1141472

Therapeutic index, ratio of plasma concentration causing emesis to IC50 for inhibition of LPS-stimulated TNFalpha release in squirrel monkey whole blood: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA945962

Ratio

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
587.72	5.87	5.87
476.60	4.71	4.71
485.61	6.04	6.04

Parent Molecular Weight

ALogP

Polar Surface Area

587.72

5.87

476.60

4.71

485.61

6.04

Therapeutic index, ratio of plasma concentration causing emesis to IC50 for inhibition of LPS-stimulated TNFalpha release in squirrel monkey whole blo...

Basic Information

Activity Charts

Compound Summary