Basic Information
ID: ALA946711
Type: Binding
Description: Inhibition of ADAMTS5 by FRET assay
Activity Charts
Bioactivity
Activity Types for Assay ALA946711
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.44 | 4.23 | 4.23 |
| 402.43 | 4.36 | 4.36 |
| 429.43 | 4.13 | 4.13 |
| 418.88 | 4.88 | 4.88 |
| 500.81 | 6.53 | 6.53 |
| 466.37 | 5.24 | 5.24 |
| 466.37 | 5.59 | 5.59 |
| 480.40 | 5.58 | 5.58 |
| 432.91 | 5.19 | 5.19 |
| 446.93 | 5.32 | 5.32 |
| 448.91 | 4.89 | 4.89 |
| 453.33 | 5.53 | 5.53 |
| 463.88 | 4.79 | 4.79 |
| 436.87 | 5.02 | 5.02 |
| 450.90 | 5.16 | 5.16 |
| 463.88 | 4.79 | 4.79 |
| 436.87 | 5.02 | 5.02 |
| 432.91 | 5.19 | 5.19 |
| 486.88 | 5.90 | 5.90 |
| 453.33 | 5.53 | 5.53 |
| 463.88 | 4.79 | 4.79 |
| 443.89 | 4.75 | 4.75 |
| 508.33 | 4.90 | 4.90 |
| 497.78 | 5.64 | 5.64 |
| 463.88 | 4.79 | 4.79 |
| 443.46 | 4.44 | 4.44 |
| 432.91 | 5.19 | 5.19 |
| 449.89 | 4.28 | 4.28 |
| 462.93 | 5.20 | 5.20 |
| 478.93 | 4.90 | 4.90 |
| 491.98 | 4.95 | 4.95 |
| 505.96 | 4.85 | 4.85 |
| 497.38 | 5.85 | 5.85 |
| 541.00 | 6.68 | 6.68 |
| 464.87 | 4.18 | 4.18 |
| 505.91 | 4.99 | 4.99 |
| 512.35 | 5.75 | 5.75 |
| 532.77 | 6.09 | 6.09 |
| 432.91 | 5.19 | 5.19 |
| 453.33 | 5.53 | 5.53 |
| 479.94 | 5.08 | 5.08 |
| 493.92 | 4.98 | 4.98 |
| 437.86 | 4.41 | 4.41 |
| 496.39 | 5.60 | 5.60 |
| 510.38 | 5.49 | 5.49 |
| 501.80 | 6.49 | 6.49 |
| 509.43 | 6.83 | 6.83 |
| 473.96 | 5.42 | 5.42 |
| 456.93 | 5.09 | 5.09 |
| 474.99 | 5.29 | 5.29 |
| 480.40 | 6.18 | 6.18 |
| 445.95 | 4.90 | 4.90 |
| 445.95 | 5.24 | 5.24 |
| 459.98 | 5.24 | 5.24 |
| 504.93 | 5.02 | 5.02 |
| 511.37 | 5.78 | 5.78 |
| 519.95 | 4.78 | 4.78 |
| 490.95 | 4.84 | 4.84 |
| 484.36 | 6.01 | 6.01 |
| 449.91 | 4.73 | 4.73 |
| 449.91 | 5.07 | 5.07 |
| 463.94 | 5.07 | 5.07 |
| 476.55 | 4.59 | 4.59 |