Basic Information
ID: ALA947249
Type: ADME
Description: Ratio of Cmax for drug to Cmax for 4'-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-ethyl}-3-isopropoxy-biphenyl-4-carboxylic acid in beagle dog at 0.1 mg/kg, po by cassette assay
Organism: Canis lupus familiaris
Activity Charts
Bioactivity
Activity Types for Assay ALA947249
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 211.26 | 1.13 | 1.13 |
| 417.55 | 5.12 | 5.12 |
| 459.59 | 5.63 | 5.63 |
| 419.52 | 4.70 | 4.70 |
| 494.03 | 6.28 | 6.28 |
| 453.97 | 5.36 | 5.36 |
| 453.97 | 5.36 | 5.36 |
| 437.51 | 4.84 | 4.84 |
| 435.52 | 4.41 | 4.41 |
| 512.63 | 4.08 | 4.08 |
| 434.54 | 4.29 | 4.29 |
| 434.54 | 4.29 | 4.29 |
| 528.63 | 3.78 | 3.78 |
| 420.51 | 4.10 | 4.10 |
| 435.52 | 3.68 | 3.68 |
| 418.54 | 4.51 | 4.51 |
| 460.57 | 5.02 | 5.02 |
| 433.55 | 4.09 | 4.09 |
| 475.59 | 4.61 | 4.61 |
| 409.91 | 4.96 | 4.96 |
| 409.91 | 4.96 | 4.96 |
| 467.99 | 5.75 | 5.75 |
| 375.47 | 4.31 | 4.31 |
| 405.49 | 4.31 | 4.31 |
| 419.52 | 4.70 | 4.70 |
| 433.55 | 5.09 | 5.09 |
| 447.58 | 5.34 | 5.34 |
| 473.61 | 6.02 | 6.02 |
| 447.58 | 5.48 | 5.48 |
| 449.55 | 4.07 | 4.07 |
| 449.55 | 4.80 | 4.80 |
| 433.55 | 5.09 | 5.09 |
| 433.55 | 5.09 | 5.09 |
| 431.58 | 5.50 | 5.50 |
| 376.46 | 3.70 | 3.70 |
| 434.54 | 4.49 | 4.49 |
| 434.54 | 4.49 | 4.49 |
| 474.60 | 5.41 | 5.41 |
| 469.97 | 5.19 | 5.19 |
| 469.97 | 5.20 | 5.20 |
| 483.99 | 5.44 | 5.44 |
| 467.99 | 5.61 | 5.61 |
| 510.03 | 6.12 | 6.12 |
| 435.52 | 4.54 | 4.54 |
| 435.52 | 4.54 | 4.54 |
| 449.55 | 4.79 | 4.79 |
| 475.59 | 5.47 | 5.47 |
| 467.99 | 5.75 | 5.75 |
| 468.98 | 5.23 | 5.23 |
| 449.55 | 3.93 | 3.93 |