Basic Information
ID: ALA948146
Type: Binding
Description: Displacement of [3H]dofetilide from human recombinant ERG potassium channel expressed in HEK293 cells by patch clamp method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: HERG(ALA240)
Document: ALA1142336
Displacement of [3H]dofetilide from human recombinant ERG potassium channel expressed in HEK293 cells by patch clamp method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA948146
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.02 | 4.23 | 4.23 |
| 439.00 | 3.34 | 3.34 |
| 538.65 | 5.19 | 5.19 |
| 487.60 | 4.64 | 4.64 |
| 457.57 | 4.63 | 4.63 |
| 487.60 | 4.64 | 4.64 |
| 583.51 | 7.01 | 7.01 |
| 338.88 | 2.68 | 2.68 |
| 487.00 | 3.93 | 3.93 |
| 442.56 | 4.79 | 4.79 |
| 565.13 | 3.49 | 3.49 |
| 458.99 | 4.29 | 4.29 |
| 459.97 | 3.69 | 3.69 |
| 441.58 | 5.39 | 5.39 |
| 396.92 | 2.47 | 2.47 |
| 505.06 | 6.66 | 6.66 |
| 458.99 | 4.29 | 4.29 |
| 474.00 | 3.99 | 3.99 |
| 487.04 | 4.08 | 4.08 |
| 488.03 | 3.48 | 3.48 |
| 475.03 | 6.65 | 6.65 |
| 391.94 | 3.30 | 3.30 |
| 487.60 | 4.64 | 4.64 |
| 487.60 | 4.64 | 4.64 |
| 471.60 | 5.40 | 5.40 |
| 471.60 | 5.40 | 5.40 |
| 441.58 | 5.39 | 5.39 |
| 451.01 | 3.48 | 3.48 |
| 505.06 | 6.66 | 6.66 |
| 514.62 | 5.70 | 5.70 |
| 475.03 | 6.65 | 6.65 |
| 486.62 | 4.98 | 4.98 |
| 504.97 | 2.00 | 2.00 |
| 486.62 | 4.98 | 4.98 |