Basic Information
ID: ALA951835
Type: Functional
Description: Antagonist activity at adenosine A2B receptor in human Jurkat T cells assessed as inhibition of NECA-induced increase in intracellular calcium concentration by fluorimetric measurement in presence of MSX-2
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Jurkat
Target: Adenosine A2b receptor(ALA255)
Document: ALA1137016
Antagonist activity at adenosine A2B receptor in human Jurkat T cells assessed as inhibition of NECA-induced increase in intracellular calcium concentration by fluorimetric measurement in presence of MSX-2: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA951835
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.60 | 2.00 | 2.00 |
| 494.58 | 1.61 | 1.61 |
| 529.02 | 2.26 | 2.26 |
| 543.05 | 2.65 | 2.65 |
| 543.05 | 2.65 | 2.65 |
| 529.02 | 2.26 | 2.26 |
| 512.57 | 1.75 | 1.75 |
| 526.59 | 2.14 | 2.14 |
| 512.57 | 1.75 | 1.75 |
| 526.59 | 2.14 | 2.14 |
| 562.57 | 2.63 | 2.63 |
| 576.60 | 3.02 | 3.02 |
| 562.57 | 2.63 | 2.63 |
| 576.60 | 3.02 | 3.02 |
| 508.60 | 1.91 | 1.91 |
| 522.63 | 2.30 | 2.30 |
| 524.60 | 1.61 | 1.61 |
| 538.63 | 2.01 | 2.01 |
| 538.59 | 1.34 | 1.34 |
| 552.61 | 1.73 | 1.73 |
| 515.00 | 2.26 | 2.26 |
| 529.02 | 2.65 | 2.65 |
| 524.99 | 1.88 | 1.88 |
| 510.58 | 1.62 | 1.62 |
| 524.60 | 2.01 | 2.01 |
| 508.60 | 1.65 | 1.65 |
| 522.63 | 2.04 | 2.04 |
| 403.46 | 1.27 | 1.27 |
| 417.49 | 1.66 | 1.66 |
| 522.63 | 2.43 | 2.43 |