Basic Information
ID: ALA954137
Type: Binding
Description: Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile tone
Activity Charts
Bioactivity
Activity Types for Assay ALA954137
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.23 | 4.06 | 4.06 |
| 248.67 | 2.69 | 2.69 |
| 254.70 | 2.75 | 2.75 |
| 265.67 | 3.44 | 3.44 |
| 211.22 | 2.13 | 2.13 |
| 262.23 | 0.86 | 0.86 |
| 277.71 | 3.31 | 3.31 |
| 225.25 | 2.19 | 2.19 |
| 282.65 | 1.21 | 1.21 |
| 278.23 | 0.56 | 0.56 |
| 261.71 | 3.61 | 3.61 |
| 265.67 | 3.44 | 3.44 |
| 268.73 | 3.06 | 3.06 |
| 248.67 | 2.69 | 2.69 |
| 297.20 | 0.66 | 0.66 |
| 259.23 | -0.35 | -0.35 |
| 248.67 | 2.69 | 2.69 |
| 263.65 | 0.29 | 0.29 |
| 320.31 | 1.20 | 1.20 |
| 314.23 | 1.57 | 1.57 |
| 247.19 | -0.22 | -0.22 |
| 258.24 | -0.16 | -0.16 |
| 248.20 | 0.56 | 0.56 |
| 229.20 | -0.36 | -0.36 |
| 312.15 | 3.96 | 3.96 |
| 291.73 | 3.61 | 3.61 |
| 265.32 | 2.62 | 2.62 |
| 263.68 | 3.00 | 3.00 |
| 253.26 | 2.13 | 2.13 |
| 285.73 | 3.22 | 3.22 |
| 288.26 | 2.56 | 2.56 |
| 272.26 | 2.86 | 2.86 |
| 417.77 | 3.58 | 3.58 |
| 298.12 | 3.66 | 3.66 |
| 288.26 | 2.56 | 2.56 |
| 299.72 | 2.86 | 2.86 |
| 322.70 | 3.21 | 3.21 |
| 274.23 | 2.26 | 2.26 |
| 239.23 | 1.83 | 1.83 |
| 307.23 | 2.84 | 2.84 |
| 273.68 | 2.48 | 2.48 |
| 272.26 | 2.86 | 2.86 |
| 282.26 | 2.55 | 2.55 |
| 257.22 | 1.96 | 1.96 |
| 258.23 | 2.55 | 2.55 |
| 291.73 | 3.70 | 3.70 |
| 315.33 | 3.49 | 3.49 |
| 326.23 | 3.57 | 3.57 |
| 306.70 | 3.51 | 3.51 |
| 308.68 | 2.91 | 2.91 |
| 334.33 | 4.22 | 4.22 |
| 292.68 | 3.21 | 3.21 |
| 299.76 | 3.28 | 3.28 |
| 274.23 | 2.26 | 2.26 |
| 305.30 | 1.30 | 1.30 |
| 227.26 | 2.95 | 2.95 |
| 248.67 | 2.69 | 2.69 |
| 276.22 | 2.69 | 2.69 |
| 271.32 | 3.35 | 3.35 |
| 245.25 | 3.09 | 3.09 |
| 253.71 | 3.36 | 3.36 |
| 248.67 | 2.69 | 2.69 |
| 282.13 | 3.95 | 3.95 |
| 262.70 | 3.00 | 3.00 |
| 257.29 | 2.96 | 2.96 |
| 236.66 | 2.63 | 2.63 |
| 247.68 | 3.30 | 3.30 |
| 243.23 | -0.05 | -0.05 |
| 237.64 | 2.89 | 2.89 |