Basic Information
ID: ALA958118
Type: Functional
Description: Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assay
Organism: Rattus norvegicus
Cell type: 1321-N1
Activity Charts
Bioactivity
Activity Types for Assay ALA958118
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 234.34 | 3.41 | 3.41 |
| 220.32 | 2.87 | 2.87 |
| 232.33 | 3.02 | 3.02 |
| 246.35 | 3.41 | 3.41 |
| 246.35 | 3.41 | 3.41 |
| 246.35 | 3.41 | 3.41 |
| 294.40 | 3.95 | 3.95 |
| 284.40 | 3.65 | 3.65 |
| 300.40 | 3.35 | 3.35 |
| 298.43 | 3.96 | 3.96 |
| 270.38 | 3.35 | 3.35 |
| 288.37 | 3.49 | 3.49 |
| 288.37 | 3.49 | 3.49 |
| 288.37 | 3.49 | 3.49 |
| 304.82 | 4.00 | 4.00 |
| 339.27 | 4.65 | 4.65 |
| 339.27 | 4.65 | 4.65 |
| 271.36 | 2.74 | 2.74 |
| 271.36 | 2.74 | 2.74 |
| 321.42 | 3.89 | 3.89 |
| 321.42 | 3.89 | 3.89 |
| 355.87 | 4.55 | 4.55 |
| 307.40 | 3.50 | 3.50 |
| 335.45 | 4.28 | 4.28 |
| 355.87 | 4.26 | 4.26 |
| 349.48 | 4.67 | 4.67 |
| 337.42 | 3.01 | 3.01 |
| 375.47 | 4.59 | 4.59 |
| 363.44 | 4.72 | 4.72 |
| 363.44 | 4.72 | 4.72 |
| 363.44 | 4.72 | 4.72 |
| 283.38 | 3.36 | 3.36 |
| 311.43 | 4.14 | 4.14 |
| 293.37 | 3.28 | 3.28 |
| 323.40 | 3.07 | 3.07 |