Basic Information
ID: ALA962058
Type: Binding
Description: Inhibition of human sodium Nav1.5 channel expressed in HEK293 cells assessed as inhibition of veratridine-induced late sodium current elicited at -30 mV from holding potential of -110 mV at 10 uM by patch clamp technique
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA962058
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.55 | 2.31 | 2.31 |
| 375.56 | 4.57 | 4.57 |
| 377.53 | 3.29 | 3.29 |
| 377.53 | 3.29 | 3.29 |
| 377.53 | 3.29 | 3.29 |
| 377.53 | 3.29 | 3.29 |
| 375.56 | 4.57 | 4.57 |
| 375.56 | 4.57 | 4.57 |
| 375.56 | 4.57 | 4.57 |
| 379.52 | 4.27 | 4.27 |
| 391.56 | 3.95 | 3.95 |
| 405.59 | 4.34 | 4.34 |
| 419.61 | 4.73 | 4.73 |
| 373.54 | 4.49 | 4.49 |
| 389.59 | 4.96 | 4.96 |
| 403.61 | 5.35 | 5.35 |
| 403.61 | 5.20 | 5.20 |
| 401.60 | 5.27 | 5.27 |
| 413.54 | 4.17 | 4.17 |
| 319.27 | -5.52 | -5.52 |