Basic Information
ID: ALA962456
Type: Binding
Description: Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone at 0.3 uM after 18 hrs
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA962456
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 286.42 | 4.09 | 4.09 |
| 416.58 | 4.85 | 4.85 |
| 342.48 | 4.59 | 4.59 |
| 358.48 | 3.85 | 3.85 |
| 328.45 | 4.12 | 4.12 |
| 326.44 | 4.32 | 4.32 |
| 340.46 | 4.71 | 4.71 |
| 354.49 | 5.10 | 5.10 |
| 382.54 | 5.74 | 5.74 |
| 398.50 | 4.11 | 4.11 |
| 338.45 | 4.49 | 4.49 |
| 338.49 | 5.25 | 5.25 |
| 352.52 | 5.64 | 5.64 |
| 344.50 | 4.67 | 4.67 |
| 400.56 | 5.18 | 5.18 |
| 326.44 | 4.32 | 4.32 |
| 342.48 | 4.77 | 4.77 |
| 354.49 | 4.96 | 4.96 |
| 368.52 | 5.35 | 5.35 |
| 354.49 | 4.96 | 4.96 |
| 380.53 | 5.52 | 5.52 |
| 312.41 | 3.79 | 3.79 |
| 326.44 | 4.18 | 4.18 |
| 340.46 | 4.57 | 4.57 |
| 326.44 | 4.18 | 4.18 |
| 324.46 | 5.01 | 5.01 |