Basic Information
ID: ALA963312
Type: Binding
Description: Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosis
Organism: Homo sapiens
Cell type: PS120
Activity Charts
Bioactivity
Activity Types for Assay ALA963312
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.46 | 0.63 | 0.63 |
| 339.38 | 0.80 | 0.80 |
| 449.51 | 1.11 | 1.11 |
| 353.40 | 1.11 | 1.11 |
| 449.51 | 1.11 | 1.11 |
| 463.54 | 1.42 | 1.42 |
| 463.54 | 1.42 | 1.42 |
| 367.43 | 1.42 | 1.42 |
| 465.51 | 0.81 | 0.81 |
| 465.51 | 0.81 | 0.81 |
| 465.51 | 0.81 | 0.81 |
| 495.54 | 0.82 | 0.82 |
| 495.54 | 0.82 | 0.82 |
| 453.47 | 0.94 | 0.94 |
| 357.37 | 0.94 | 0.94 |
| 453.47 | 0.94 | 0.94 |
| 471.46 | 1.08 | 1.08 |
| 471.46 | 1.08 | 1.08 |
| 375.36 | 1.08 | 1.08 |
| 469.93 | 1.45 | 1.45 |
| 373.82 | 1.45 | 1.45 |
| 469.93 | 1.45 | 1.45 |
| 504.37 | 2.11 | 2.11 |
| 504.37 | 2.11 | 2.11 |
| 408.27 | 2.11 | 2.11 |
| 499.96 | 1.46 | 1.46 |
| 483.50 | 0.95 | 0.95 |
| 340.36 | 1.06 | 1.06 |
| 354.39 | 1.37 | 1.37 |
| 368.42 | 1.68 | 1.68 |
| 368.42 | 1.68 | 1.68 |
| 358.35 | 1.20 | 1.20 |
| 376.34 | 1.34 | 1.34 |
| 376.34 | 1.34 | 1.34 |
| 374.81 | 1.72 | 1.72 |
| 374.81 | 1.72 | 1.72 |
| 409.25 | 2.37 | 2.37 |
| 409.25 | 2.37 | 2.37 |