Basic Information
ID: ALA968750
Type: Functional
Description: Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin luminescence assay
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA968750
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.48 | 5.25 | 5.25 |
| 305.38 | 3.58 | 3.58 |
| 383.46 | 4.04 | 4.04 |
| 411.51 | 5.26 | 5.26 |
| 427.51 | 4.44 | 4.44 |
| 385.46 | 3.78 | 3.78 |
| 363.44 | 4.31 | 4.31 |
| 281.33 | 4.14 | 4.14 |
| 384.28 | 4.35 | 4.35 |
| 382.47 | 4.64 | 4.64 |
| 382.47 | 4.64 | 4.64 |
| 382.47 | 4.64 | 4.64 |
| 383.45 | 4.04 | 4.04 |
| 398.47 | 3.94 | 3.94 |
| 417.53 | 4.80 | 4.80 |
| 367.50 | 5.61 | 5.61 |
| 382.47 | 4.19 | 4.19 |
| 353.43 | 4.47 | 4.47 |
| 401.90 | 4.43 | 4.43 |
| 387.53 | 5.63 | 5.63 |
| 388.52 | 4.57 | 4.57 |
| 390.49 | 3.42 | 3.42 |
| 411.51 | 5.26 | 5.26 |
| 465.48 | 6.15 | 6.15 |
| 424.50 | 4.35 | 4.35 |
| 387.53 | 5.24 | 5.24 |
| 382.47 | 4.64 | 4.64 |
| 395.51 | 5.26 | 5.26 |
| 382.46 | 5.51 | 5.51 |
| 331.42 | 4.10 | 4.10 |
| 308.38 | 2.69 | 2.69 |
| 345.45 | 4.17 | 4.17 |
| 395.51 | 5.32 | 5.32 |
| 367.47 | 3.65 | 3.65 |
| 381.50 | 3.72 | 3.72 |
| 431.56 | 4.87 | 4.87 |
| 349.41 | 4.24 | 4.24 |
| 337.81 | 4.79 | 4.79 |