Basic Information
ID: ALA968795
Type: Functional
Description: Antagonist activity at human cloned P2X7 receptor expressed in HEK293 cells assessed as inhibition of calcium flux by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: P2X purinoceptor 7(ALA4805)
Document: ALA1138502
Antagonist activity at human cloned P2X7 receptor expressed in HEK293 cells assessed as inhibition of calcium flux by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA968795
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.15 | 4.18 | 4.18 |
| 455.73 | 3.53 | 3.53 |
| 437.54 | 3.58 | 3.58 |
| 474.57 | 3.82 | 3.82 |
| 474.57 | 3.82 | 3.82 |
| 441.51 | 3.41 | 3.41 |
| 423.59 | 4.29 | 4.29 |
| 421.50 | 3.29 | 3.29 |
| 411.94 | 4.22 | 4.22 |
| 407.52 | 3.57 | 3.57 |
| 437.54 | 3.58 | 3.58 |
| 357.50 | 3.90 | 3.90 |
| 377.49 | 3.56 | 3.56 |
| 423.52 | 3.65 | 3.65 |
| 423.52 | 3.65 | 3.65 |
| 393.49 | 3.64 | 3.64 |
| 451.57 | 3.97 | 3.97 |
| 421.55 | 3.96 | 3.96 |
| 435.57 | 4.35 | 4.35 |
| 405.55 | 4.34 | 4.34 |
| 424.57 | 3.68 | 3.68 |
| 412.93 | 3.61 | 3.61 |
| 410.50 | 3.41 | 3.41 |
| 396.47 | 3.10 | 3.10 |
| 436.56 | 3.75 | 3.75 |
| 420.56 | 4.13 | 4.13 |
| 448.96 | 4.46 | 4.46 |
| 460.61 | 4.53 | 4.53 |
| 472.55 | 3.58 | 3.58 |
| 464.57 | 4.96 | 4.96 |
| 439.52 | 3.68 | 3.68 |
| 443.56 | 3.98 | 3.98 |
| 495.37 | 2.82 | 2.82 |
| 481.34 | 2.90 | 2.90 |
| 309.41 | 4.11 | 4.11 |
| 490.84 | 4.35 | 4.35 |
| 485.76 | 3.54 | 3.54 |
| 465.34 | 3.20 | 3.20 |
| 484.56 | 2.69 | 2.69 |
| 451.57 | 3.89 | 3.89 |
| 457.96 | 3.93 | 3.93 |
| 475.95 | 4.07 | 4.07 |
| 459.50 | 3.55 | 3.55 |
| 477.49 | 3.69 | 3.69 |
| 458.95 | 3.32 | 3.32 |
| 454.53 | 2.68 | 2.68 |
| 453.54 | 3.28 | 3.28 |
| 441.51 | 3.41 | 3.41 |
| 459.50 | 3.55 | 3.55 |
| 459.50 | 3.55 | 3.55 |
| 474.57 | 3.82 | 3.82 |
| 438.53 | 2.98 | 2.98 |
| 441.51 | 3.41 | 3.41 |
| 459.50 | 3.55 | 3.55 |
| 459.50 | 3.55 | 3.55 |
| 471.99 | 3.60 | 3.60 |
| 459.50 | 3.55 | 3.55 |
| 437.54 | 3.58 | 3.58 |
| 437.54 | 3.58 | 3.58 |