Basic Information
ID: ALA970524
Type: Binding
Description: Inhibition of ASIC3 at 20 uM assessed as inhibition of peak current by patch clamp electrophysiology relative to baseline
Activity Charts
Bioactivity
Activity Types for Assay ALA970524
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.63 | -1.08 | -1.08 |
| 269.70 | -0.28 | -0.28 |
| 271.71 | -0.05 | -0.05 |
| 325.80 | 0.89 | 0.89 |
| 311.78 | 0.72 | 0.72 |
| 285.74 | 0.34 | 0.34 |
| 311.65 | 0.10 | 0.10 |
| 269.70 | -0.30 | -0.30 |
| 311.78 | 0.87 | 0.87 |
| 325.80 | 1.12 | 1.12 |
| 257.68 | -0.60 | -0.60 |
| 285.74 | -0.03 | -0.03 |
| 283.72 | -0.27 | -0.27 |
| 297.75 | 0.12 | 0.12 |
| 312.77 | -1.12 | -1.12 |
| 299.72 | -1.04 | -1.04 |
| 331.77 | 0.82 | 0.82 |
| 345.79 | 0.69 | 0.69 |
| 305.73 | 0.87 | 0.87 |
| 373.73 | 1.89 | 1.89 |
| 340.17 | 1.52 | 1.52 |
| 306.72 | 0.26 | 0.26 |
| 306.72 | 0.26 | 0.26 |
| 356.78 | 1.42 | 1.42 |
| 355.79 | 2.02 | 2.02 |
| 356.78 | 1.42 | 1.42 |
| 337.75 | 0.88 | 0.88 |
| 354.20 | 1.39 | 1.39 |
| 354.20 | 1.39 | 1.39 |
| 369.82 | 1.89 | 1.89 |
| 373.85 | 1.34 | 1.34 |
| 337.75 | 0.88 | 0.88 |
| 333.78 | 0.99 | 0.99 |
| 351.77 | 0.92 | 0.92 |
| 351.77 | 0.92 | 0.92 |
| 351.77 | 0.92 | 0.92 |
| 230.62 | -1.17 | -1.17 |
| 244.64 | -0.87 | -0.87 |
| 370.80 | 1.86 | 1.86 |
| 260.71 | -0.15 | -0.15 |
| 322.78 | 1.28 | 1.28 |
| 306.71 | 0.92 | 0.92 |
| 356.77 | 2.07 | 2.07 |
| 372.84 | 2.43 | 2.43 |
| 357.76 | 1.47 | 1.47 |
| 357.76 | 1.47 | 1.47 |
| 357.76 | 1.47 | 1.47 |
| 256.27 | 0.14 | 0.14 |
| 262.30 | 0.20 | 0.20 |
| 306.33 | 1.29 | 1.29 |
| 306.33 | 1.29 | 1.29 |
| 270.30 | 0.06 | 0.06 |
| 284.32 | 0.76 | 0.76 |
| 332.37 | 1.81 | 1.81 |
| 338.40 | 1.87 | 1.87 |
| 332.37 | 1.81 | 1.81 |
| 332.37 | 1.81 | 1.81 |
| 322.33 | 1.40 | 1.40 |