Basic Information
ID: ALA970539
Type: Binding
Description: Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoazetidin-2-yl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid from human recombinant NPC1L1 expressed in HEK293 cells
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA970539
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 585.56 | 2.45 | 2.45 |
| 622.62 | -0.38 | -0.38 |
| 462.59 | 5.27 | 5.27 |
| 504.68 | 4.04 | 4.04 |
| 561.77 | 7.75 | 7.75 |
| 575.73 | 5.19 | 5.19 |
| 460.58 | 4.50 | 4.50 |
| 594.70 | 7.74 | 7.74 |
| 516.69 | 4.28 | 4.28 |
| 526.68 | 6.67 | 6.67 |