Basic Information
ID: ALA972377
Type: Binding
Description: Inhibition of HCV 1b J4 recombinant NS5B Cdelta 21 polymerase overexpressed in Escherichia coli BL21 (DE3) assessed as [alpha33P]UTP incorporation by scintillation proximity analysis
Organism: Hepatitis C virus subtype 1b
Strain: J4
Activity Charts
Bioactivity
Activity Types for Assay ALA972377
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.35 | 6.16 | 6.16 |
| 454.36 | 6.03 | 6.03 |
| 443.37 | 6.46 | 6.46 |
| 508.24 | 6.92 | 6.92 |
| 445.35 | 5.86 | 5.86 |
| 445.35 | 5.86 | 5.86 |
| 445.35 | 5.86 | 5.86 |
| 430.34 | 5.55 | 5.55 |
| 430.34 | 5.55 | 5.55 |
| 431.32 | 4.95 | 4.95 |
| 447.32 | 4.65 | 4.65 |
| 501.03 | 7.08 | 7.08 |
| 517.03 | 6.79 | 6.79 |
| 503.00 | 7.00 | 7.00 |
| 581.89 | 7.76 | 7.76 |
| 599.88 | 7.90 | 7.90 |
| 366.42 | 4.15 | 4.15 |
| 377.44 | 3.95 | 3.95 |
| 380.45 | 3.29 | 3.29 |
| 429.52 | 5.05 | 5.05 |
| 488.61 | 6.20 | 6.20 |
| 382.50 | 4.76 | 4.76 |
| 300.36 | 2.81 | 2.81 |
| 545.08 | 7.42 | 7.42 |
| 528.62 | 6.91 | 6.91 |
| 589.53 | 7.53 | 7.53 |
| 524.66 | 7.08 | 7.08 |
| 563.63 | 6.96 | 6.96 |
| 563.63 | 6.96 | 6.96 |
| 563.63 | 6.96 | 6.96 |
| 577.66 | 7.27 | 7.27 |
| 577.66 | 7.27 | 7.27 |
| 577.66 | 7.27 | 7.27 |
| 581.62 | 7.10 | 7.10 |
| 598.07 | 7.62 | 7.62 |
| 552.60 | 7.16 | 7.16 |
| 569.66 | 7.02 | 7.02 |
| 569.66 | 7.02 | 7.02 |
| 583.69 | 7.33 | 7.33 |
| 567.62 | 6.86 | 6.86 |
| 581.64 | 7.17 | 7.17 |
| 581.64 | 7.17 | 7.17 |
| 581.64 | 7.17 | 7.17 |
| 567.62 | 6.86 | 6.86 |
| 580.66 | 6.61 | 6.61 |
| 553.59 | 5.69 | 5.69 |
| 564.62 | 6.36 | 6.36 |
| 501.03 | 7.08 | 7.08 |