Basic Information
ID: ALA972422
Type: ADME
Description: Inhibition of CYP2C8 in human liver microsomes using montelukast substrate
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA972422
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.40 | 3.15 | 3.15 |
| 391.43 | 3.16 | 3.16 |
| 375.38 | 3.69 | 3.69 |
| 378.38 | 3.42 | 3.42 |
| 376.37 | 3.96 | 3.96 |
| 377.40 | 2.95 | 2.95 |
| 376.37 | 2.86 | 2.86 |
| 365.41 | 3.82 | 3.82 |
| 364.36 | 3.22 | 3.22 |
| 416.43 | 3.67 | 3.67 |
| 359.39 | 3.99 | 3.99 |
| 382.42 | 3.11 | 3.11 |
| 380.40 | 3.65 | 3.65 |
| 398.39 | 3.79 | 3.79 |
| 414.85 | 4.30 | 4.30 |
| 379.42 | 3.15 | 3.15 |
| 385.45 | 3.22 | 3.22 |
| 368.39 | 2.72 | 2.72 |
| 371.42 | 2.83 | 2.83 |