Assay Report Card

Basic Information

ID: ALA974347

Type: Functional

Description: Inhibition of MMP13-induced cartilage degradation in rat assessed as chondroitin sulfate release at 10 mg/kg, po administered 4 hrs before MMP13 challenge injected intra-articularly measured after 2 hrs by ELISA

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
425.893.213.21
510.633.803.80