Basic Information
ID: ALA976122
Type: Functional
Description: Antagonist activity at human MC4R expressed in CHO cells assessed as inhibition of alpha-MSH-induced cAMP production by ELISA
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA976122
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.01 | 4.97 | 4.97 |
| 442.05 | 5.14 | 5.14 |
| 428.02 | 4.83 | 4.83 |
| 503.11 | 4.82 | 4.82 |
| 517.09 | 4.35 | 4.35 |
| 545.14 | 5.08 | 5.08 |
| 541.18 | 5.25 | 5.25 |
| 527.15 | 4.94 | 4.94 |
| 513.13 | 4.60 | 4.60 |
| 499.10 | 4.34 | 4.34 |
| 431.98 | 4.66 | 4.66 |
| 448.44 | 5.18 | 5.18 |
| 413.99 | 4.52 | 4.52 |
| 537.51 | 4.69 | 4.69 |
| 531.12 | 4.77 | 4.77 |
| 545.10 | 4.05 | 4.05 |
| 519.52 | 4.55 | 4.55 |
| 545.55 | 4.90 | 4.90 |
| 513.13 | 4.63 | 4.63 |
| 462.01 | 4.67 | 4.67 |
| 466.43 | 5.32 | 5.32 |
| 489.08 | 4.51 | 4.51 |
| 503.06 | 4.04 | 4.04 |
| 533.09 | 4.05 | 4.05 |
| 549.54 | 4.56 | 4.56 |
| 549.54 | 4.69 | 4.69 |
| 547.57 | 5.29 | 5.29 |
| 561.55 | 4.56 | 4.56 |