Basic Information
ID: ALA976298
Type: Binding
Description: Inhibition of human wild type CFTR expressed in rat FRT cells assessed as chloride current by short-circuit current measurements
Format: BAO_0000219
Organism: Homo sapiens
Cell type: FRT
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA1139397
Inhibition of human wild type CFTR expressed in rat FRT cells assessed as chloride current by short-circuit current measurements: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA976298
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.47 | 4.79 | 4.79 |
| 423.44 | 4.81 | 4.81 |
| 393.34 | 4.64 | 4.64 |
| 417.37 | 4.13 | 4.13 |
| 410.74 | 3.84 | 3.84 |
| 395.36 | 3.83 | 3.83 |
| 456.49 | 4.58 | 4.58 |
| 514.53 | 4.12 | 4.12 |
| 472.49 | 4.28 | 4.28 |
| 504.49 | 3.72 | 3.72 |
| 411.43 | 4.38 | 4.38 |
| 364.35 | 5.27 | 5.27 |
| 380.35 | 4.98 | 4.98 |
| 365.34 | 4.67 | 4.67 |
| 381.34 | 4.37 | 4.37 |
| 333.27 | 3.65 | 3.65 |
| 333.27 | 3.65 | 3.65 |
| 427.40 | 4.95 | 4.95 |
| 409.41 | 4.81 | 4.81 |
| 433.44 | 4.29 | 4.29 |
| 425.41 | 4.52 | 4.52 |
| 409.41 | 4.81 | 4.81 |
| 439.44 | 4.57 | 4.57 |
| 427.40 | 4.95 | 4.95 |
| 355.44 | 4.10 | 4.10 |
| 369.47 | 4.41 | 4.41 |
| 539.19 | 6.34 | 6.34 |
| 555.19 | 6.05 | 6.05 |
| 382.39 | 3.74 | 3.74 |
| 423.44 | 5.12 | 5.12 |
| 413.40 | 4.23 | 4.23 |
| 409.41 | 4.81 | 4.81 |
| 409.41 | 4.81 | 4.81 |
| 425.41 | 4.52 | 4.52 |
| 477.41 | 5.83 | 5.83 |
| 443.86 | 5.46 | 5.46 |
| 409.41 | 4.81 | 4.81 |
| 409.41 | 4.81 | 4.81 |
| 409.41 | 4.81 | 4.81 |
| 409.41 | 4.81 | 4.81 |
| 409.41 | 4.81 | 4.81 |
| 443.86 | 5.46 | 5.46 |
| 381.40 | 4.82 | 4.82 |
| 425.41 | 4.52 | 4.52 |
| 366.39 | 4.51 | 4.51 |
| 413.40 | 4.23 | 4.23 |
| 467.45 | 4.36 | 4.36 |
| 439.44 | 4.57 | 4.57 |
| 569.49 | 3.60 | 3.60 |
| 397.40 | 4.52 | 4.52 |
| 569.22 | 6.35 | 6.35 |
| 474.32 | 5.88 | 5.88 |
| 395.43 | 5.12 | 5.12 |
| 408.43 | 4.21 | 4.21 |
| 452.48 | 3.83 | 3.83 |
| 451.50 | 3.80 | 3.80 |
| 437.46 | 5.29 | 5.29 |