Basic Information
ID: ALA980875
Type: Functional
Description: Antibone resorptive activity in Sprague-Dawley rat assessed as inhibition of cathepsin K-mediated C-terminal telopeptidase of type 1 collagen degradation at 100 mg/kg/day, po for 11 days measured on 24 hrs after final administration by RatLaps ELISA
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA980875
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.49 | 1.87 | 1.87 |
| 437.55 | 2.65 | 2.65 |
| 394.48 | 1.98 | 1.98 |
| 446.53 | 3.66 | 3.66 |
| 395.47 | 1.52 | 1.52 |
| 458.57 | 3.53 | 3.53 |
| 437.55 | 2.65 | 2.65 |