Basic Information
ID: ALA981002
Type: Binding
Description: Inhibition of BRAF V600E mutant
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase B-raf(ALA5145)
Document: ALA1153434
Inhibition of BRAF V600E mutant: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA981002
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.83 | 5.55 | 5.55 |
| 463.80 | 5.36 | 5.36 |
| 361.36 | 3.69 | 3.69 |
| 395.81 | 4.34 | 4.34 |
| 463.80 | 5.36 | 5.36 |
| 429.36 | 4.71 | 4.71 |
| 429.36 | 4.71 | 4.71 |
| 429.36 | 4.71 | 4.71 |
| 445.36 | 4.59 | 4.59 |
| 459.38 | 4.71 | 4.71 |
| 493.83 | 5.37 | 5.37 |
| 447.35 | 4.85 | 4.85 |
| 379.35 | 3.83 | 3.83 |
| 464.46 | 3.66 | 3.66 |
| 514.46 | 4.54 | 4.54 |
| 477.83 | 5.37 | 5.37 |
| 431.50 | 5.00 | 5.00 |
| 477.83 | 5.37 | 5.37 |
| 431.50 | 5.00 | 5.00 |
| 461.38 | 4.86 | 4.86 |
| 491.86 | 5.38 | 5.38 |
| 519.91 | 6.35 | 6.35 |
| 463.42 | 5.20 | 5.20 |
| 445.43 | 5.07 | 5.07 |
| 479.87 | 5.72 | 5.72 |
| 479.87 | 5.52 | 5.52 |
| 346.35 | 3.30 | 3.30 |
| 448.79 | 4.97 | 4.97 |
| 414.34 | 4.31 | 4.31 |
| 425.24 | 4.06 | 4.06 |
| 430.34 | 4.19 | 4.19 |
| 449.44 | 3.27 | 3.27 |
| 360.37 | 3.22 | 3.22 |
| 390.40 | 3.23 | 3.23 |
| 396.35 | 3.50 | 3.50 |
| 444.37 | 4.12 | 4.12 |
| 428.37 | 4.24 | 4.24 |
| 484.84 | 4.52 | 4.52 |
| 382.40 | 2.84 | 2.84 |
| 416.85 | 3.50 | 3.50 |
| 450.40 | 3.86 | 3.86 |
| 400.39 | 2.98 | 2.98 |
| 388.43 | 2.91 | 2.91 |
| 400.39 | 2.98 | 2.98 |