Basic Information
ID: ALA982605
Type: Functional
Description: Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay
Organism: Macaca fascicularis
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA982605
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.63 | 3.56 | 3.56 |
| 467.53 | 2.59 | 2.59 |
| 397.48 | 3.44 | 3.44 |
| 417.56 | 2.94 | 2.94 |
| 423.52 | 3.71 | 3.71 |
| 454.53 | 2.56 | 2.56 |
| 474.61 | 2.05 | 2.05 |
| 480.57 | 2.82 | 2.82 |
| 482.59 | 3.34 | 3.34 |
| 502.66 | 2.83 | 2.83 |
| 468.56 | 2.90 | 2.90 |
| 488.64 | 2.40 | 2.40 |
| 482.59 | 3.29 | 3.29 |
| 502.66 | 2.79 | 2.79 |
| 496.62 | 3.68 | 3.68 |
| 516.69 | 3.18 | 3.18 |
| 496.62 | 3.68 | 3.68 |
| 438.49 | 3.72 | 3.72 |
| 516.69 | 3.17 | 3.17 |
| 468.56 | 2.95 | 2.95 |
| 488.64 | 2.44 | 2.44 |
| 494.60 | 3.21 | 3.21 |
| 508.63 | 3.68 | 3.68 |
| 528.70 | 3.18 | 3.18 |
| 534.66 | 3.95 | 3.95 |
| 494.60 | 3.43 | 3.43 |
| 514.67 | 2.93 | 2.93 |
| 494.60 | 3.43 | 3.43 |
| 514.67 | 2.93 | 2.93 |
| 468.61 | 3.65 | 3.65 |
| 488.68 | 3.14 | 3.14 |
| 455.52 | 2.57 | 2.57 |
| 483.57 | 3.17 | 3.17 |
| 437.50 | 3.34 | 3.34 |
| 494.60 | 3.17 | 3.17 |
| 494.56 | 3.83 | 3.83 |
| 478.56 | 3.66 | 3.66 |
| 489.58 | 4.54 | 4.54 |
| 490.57 | 3.93 | 3.93 |
| 509.65 | 4.46 | 4.46 |
| 495.61 | 4.60 | 4.60 |
| 478.56 | 3.86 | 3.86 |
| 480.53 | 2.65 | 2.65 |
| 473.62 | 3.54 | 3.54 |
| 460.58 | 3.62 | 3.62 |
| 459.59 | 3.15 | 3.15 |
| 461.52 | 2.31 | 2.31 |
| 438.49 | 3.72 | 3.72 |