Basic Information
ID: ALA982857
Type: Functional
Description: Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA982857
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 497.60 | 4.39 | 4.39 |
| 498.59 | 4.85 | 4.85 |
| 472.98 | 5.49 | 5.49 |
| 487.01 | 5.51 | 5.51 |
| 494.02 | 4.65 | 4.65 |
| 443.98 | 5.46 | 5.46 |
| 491.98 | 5.73 | 5.73 |
| 491.00 | 5.09 | 5.09 |
| 448.95 | 5.77 | 5.77 |
| 438.96 | 4.77 | 4.77 |
| 438.96 | 4.77 | 4.77 |
| 475.98 | 5.01 | 5.01 |
| 475.98 | 5.01 | 5.01 |
| 463.97 | 4.94 | 4.94 |
| 497.99 | 5.66 | 5.66 |
| 448.51 | 3.83 | 3.83 |
| 448.50 | 4.70 | 4.70 |
| 516.05 | 5.24 | 5.24 |
| 513.01 | 5.07 | 5.07 |
| 459.94 | 4.57 | 4.57 |
| 463.56 | 4.31 | 4.31 |
| 480.02 | 4.11 | 4.11 |
| 490.01 | 5.32 | 5.32 |