Basic Information
ID: ALA986428
Type: Binding
Description: Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor
Format: BAO_0000019
Organism: Rattus norvegicus
Target: Dihydrofolate reductase(ALA2363)
Document: ALA1155823
Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA986428
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 369.43 | 2.74 | 2.74 |
| 331.40 | 2.60 | 2.60 |
| 345.43 | 2.85 | 2.85 |
| 285.38 | 2.84 | 2.84 |
| 327.46 | 3.84 | 3.84 |
| 299.40 | 3.23 | 3.23 |
| 329.43 | 3.23 | 3.23 |
| 359.46 | 3.24 | 3.24 |
| 359.46 | 3.24 | 3.24 |
| 349.46 | 4.38 | 4.38 |
| 349.46 | 4.38 | 4.38 |
| 368.29 | 4.70 | 4.70 |
| 327.46 | 4.01 | 4.01 |
| 299.40 | 3.40 | 3.40 |
| 329.43 | 3.41 | 3.41 |
| 359.46 | 3.41 | 3.41 |
| 359.46 | 3.41 | 3.41 |
| 349.46 | 4.55 | 4.55 |
| 349.46 | 4.55 | 4.55 |
| 368.29 | 4.70 | 4.70 |
| 472.53 | 2.27 | 2.27 |
| 486.55 | 2.37 | 2.37 |
| 368.29 | 4.53 | 4.53 |