Basic Information
ID: ALA987298
Type: Binding
Description: Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl}methyl)amino]carbonyl}benzoic acid from human p38alpha by fluorescence polarization
Format: BAO_0000357
Organism: Homo sapiens
Target: MAP kinase p38 alpha(ALA260)
Document: ALA1155813
Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl}methyl)amino]carbonyl}benzoic acid from human p38alpha by fluorescence polarization: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA987298
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.40 | 3.08 | 3.08 |
| 527.67 | 5.99 | 5.99 |
| 394.43 | 5.14 | 5.14 |
| 461.52 | 6.05 | 6.05 |
| 384.48 | 5.05 | 5.05 |
| 384.48 | 5.05 | 5.05 |
| 374.44 | 4.65 | 4.65 |
| 483.62 | 4.20 | 4.20 |
| 348.45 | 3.69 | 3.69 |
| 419.91 | 5.10 | 5.10 |
| 428.54 | 4.52 | 4.52 |
| 454.57 | 5.05 | 5.05 |
| 468.60 | 5.44 | 5.44 |
| 470.57 | 4.29 | 4.29 |
| 482.63 | 5.69 | 5.69 |
| 440.55 | 5.02 | 5.02 |
| 454.57 | 5.27 | 5.27 |
| 456.59 | 5.52 | 5.52 |
| 454.57 | 5.41 | 5.41 |
| 482.63 | 6.19 | 6.19 |
| 398.51 | 5.36 | 5.36 |
| 477.61 | 6.46 | 6.46 |
| 450.54 | 6.31 | 6.31 |
| 440.59 | 6.35 | 6.35 |
| 508.58 | 7.10 | 7.10 |
| 488.55 | 6.00 | 6.00 |