Basic Information
ID: ALA988266
Type: Binding
Description: Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect on foam cell formation
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA988266
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.73 | 7.29 | 7.29 |
| 358.57 | 6.01 | 6.01 |
| 416.61 | 5.64 | 5.64 |
| 430.63 | 6.42 | 6.42 |
| 416.61 | 5.86 | 5.86 |
| 416.61 | 5.86 | 5.86 |
| 387.61 | 5.47 | 5.47 |
| 440.64 | 5.11 | 5.11 |