Basic Information
ID: ALA993349
Type: Binding
Description: Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells at 100 uM by confocal microscopy
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA993349
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 162.24 | 1.85 | 1.85 |
| 361.37 | 1.54 | 1.54 |
| 264.37 | 3.08 | 3.08 |
| 280.42 | 3.88 | 3.88 |
| 441.55 | 4.37 | 4.37 |
| 284.75 | 3.15 | 3.15 |
| 267.37 | 1.61 | 1.61 |
| 252.27 | 1.77 | 1.77 |
| 314.86 | 4.53 | 4.53 |
| 290.32 | 1.26 | 1.26 |
| 454.61 | 5.09 | 5.09 |
| 398.40 | 3.70 | 3.70 |
| 414.53 | 3.37 | 3.37 |
| 266.34 | 0.45 | 0.45 |
| 180.16 | 1.31 | 1.31 |
| 259.35 | 2.58 | 2.58 |
| 252.35 | 0.60 | 0.60 |
| 297.75 | -0.35 | -0.35 |
| 330.75 | 1.89 | 1.89 |
| 581.67 | 1.99 | 1.99 |
| 232.24 | 0.70 | 0.70 |
| 326.83 | 3.72 | 3.72 |
| 429.52 | 0.81 | 0.81 |
| 393.47 | 4.51 | 4.51 |
| 293.37 | 3.13 | 3.13 |
| 385.51 | 2.09 | 2.09 |
| 211.22 | 0.44 | 0.44 |
| 267.33 | 2.85 | 2.85 |
| 375.87 | 4.43 | 4.43 |
| 153.18 | 0.60 | 0.60 |
| 286.42 | 4.09 | 4.09 |
| 272.37 | 1.09 | 1.09 |
| 494.01 | 3.64 | 3.64 |
| 285.34 | 1.20 | 1.20 |
| 299.37 | 1.50 | 1.50 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 319.88 | 4.81 | 4.81 |
| 234.34 | 2.58 | 2.58 |
| 371.52 | 6.00 | 6.00 |
| 410.49 | 3.59 | 3.59 |
| 299.80 | 2.00 | 2.00 |
| 853.92 | 3.74 | 3.74 |
| 261.09 | 1.88 | 1.88 |
| 316.43 | 0.50 | 0.50 |
| 160.18 | 0.92 | 0.92 |
| 111.15 | -0.09 | -0.09 |
| 136.15 | 0.44 | 0.44 |
| 244.89 | 0.43 | 0.43 |
| 339.48 | 3.36 | 3.36 |
| 206.28 | 3.07 | 3.07 |
| 178.27 | 3.64 | 3.64 |
| 733.94 | 1.79 | 1.79 |
| 314.47 | 4.72 | 4.72 |
| 344.85 | 5.38 | 5.38 |
| 265.35 | 1.99 | 1.99 |
| 324.40 | 3.81 | 3.81 |
| 208.26 | 1.16 | 1.16 |
| 399.44 | 2.87 | 2.87 |
| 236.27 | 3.39 | 3.39 |
| 144.21 | 2.29 | 2.29 |
| 284.43 | 4.24 | 4.24 |
| 151.16 | 1.35 | 1.35 |
| 194.19 | -1.03 | -1.03 |
| 356.42 | 4.37 | 4.37 |
| 254.29 | 3.11 | 3.11 |
| 376.45 | 1.60 | 1.60 |
| 613.80 | 2.87 | 2.87 |
| 381.38 | 3.51 | 3.51 |
| 471.69 | 6.45 | 6.45 |
| 336.48 | 4.14 | 4.14 |
| 163.20 | -0.49 | -0.49 |
| 77.15 | -0.13 | -0.13 |
| 341.41 | 1.53 | 1.53 |
| 339.39 | 3.86 | 3.86 |
| 387.44 | 1.06 | 1.06 |
| 188.23 | 1.48 | 1.48 |
| 277.41 | 4.17 | 4.17 |
| 341.45 | 3.24 | 3.24 |
| 358.43 | 1.77 | 1.77 |
| 267.24 | -0.20 | -0.20 |
| 323.13 | 0.91 | 0.91 |
| 235.33 | 1.34 | 1.34 |
| 336.43 | 2.37 | 2.37 |
| 284.43 | 4.24 | 4.24 |
| 294.44 | 4.12 | 4.12 |
| 230.10 | 2.36 | 2.36 |
| 272.39 | 3.61 | 3.61 |
| 360.84 | 4.68 | 4.68 |
| 183.21 | 0.35 | 0.35 |
| 296.15 | 4.36 | 4.36 |
| 182.17 | -3.59 | -3.59 |
| 213.66 | 1.86 | 1.86 |
| 451.48 | 1.72 | 1.72 |
| 437.53 | 4.31 | 4.31 |
| 373.95 | 4.58 | 4.58 |
| 303.83 | 4.19 | 4.19 |
| 274.40 | 3.49 | 3.49 |
| 295.38 | 1.53 | 1.53 |
| 183.21 | 0.39 | 0.39 |
| 211.26 | 1.13 | 1.13 |
| 454.45 | 0.27 | 0.27 |
| 276.21 | 3.21 | 3.21 |
| 179.31 | 2.69 | 2.69 |
| 182.17 | -0.23 | -0.23 |
| 477.05 | 5.09 | 5.09 |
| 588.56 | 1.34 | 1.34 |
| 1449.27 | ||
| 810.99 | 3.99 | 3.99 |
| 1202.63 | ||
| 302.41 | 3.62 | 3.62 |
| 285.37 | 2.20 | 2.20 |
| 269.39 | 3.66 | 3.66 |
| 337.46 | -0.77 | -0.77 |
| 303.20 | 1.94 | 1.94 |
| 315.87 | 5.19 | 5.19 |
| 434.53 | 4.60 | 4.60 |
| 104.17 | -0.32 | -0.32 |
| 171.24 | 1.37 | 1.37 |
| 229.63 | -1.08 | -1.08 |
| 130.19 | -1.00 | -1.00 |
| 113.12 | -1.02 | -1.02 |
| 382.89 | 4.89 | 4.89 |
| 388.90 | 3.15 | 3.15 |
| 197.19 | 0.05 | 0.05 |
| 440.46 | 4.03 | 4.03 |
| 418.57 | 4.59 | 4.59 |
| 445.55 | 2.08 | 2.08 |
| 277.37 | 1.72 | 1.72 |
| 363.46 | 3.39 | 3.39 |
| 172.24 | -1.27 | -1.27 |
| 424.53 | 2.44 | 2.44 |
| 346.47 | 2.67 | 2.67 |
| 247.28 | 0.53 | 0.53 |
| 357.49 | 3.34 | 3.34 |
| 260.33 | 2.02 | 2.02 |
| 374.91 | 4.04 | 4.04 |
| 452.60 | 5.22 | 5.22 |
| 324.42 | 3.17 | 3.17 |
| 531.44 | 4.21 | 4.21 |
| 324.42 | 3.17 | 3.17 |
| 349.41 | 0.32 | 0.32 |
| 572.88 | 6.11 | 6.11 |
| 430.54 | 2.72 | 2.72 |
| 169.57 | 1.77 | 1.77 |
| 416.58 | 4.85 | 4.85 |
| 822.95 | 4.34 | 4.34 |
| 255.23 | -1.97 | -1.97 |
| 225.21 | -1.33 | -1.33 |
| 130.08 | -0.80 | -0.80 |
| 129.17 | -1.03 | -1.03 |
| 444.44 | -0.35 | -0.35 |
| 332.31 | -3.58 | -3.58 |
| 444.44 | -0.21 | -0.21 |
| 315.68 | 4.07 | 4.07 |
| 180.17 | -1.04 | -1.04 |
| 308.33 | 3.61 | 3.61 |
| 136.11 | 0.06 | 0.06 |
| 384.26 | 3.96 | 3.96 |
| 301.47 | 4.33 | 4.33 |
| 114.17 | 0.71 | 0.71 |
| 277.27 | 1.15 | 1.15 |
| 217.29 | 0.63 | 0.63 |
| 289.38 | 1.93 | 1.93 |
| 645.61 | -8.56 | -8.56 |
| 441.40 | -0.04 | -0.04 |
| 317.39 | 2.28 | 2.28 |
| 537.70 | 2.37 | 2.37 |
| 390.96 | 5.56 | 5.56 |
| 417.46 | 1.72 | 1.72 |
| 776.87 | 4.56 | 4.56 |
| 343.90 | 5.10 | 5.10 |
| 424.59 | 5.08 | 5.08 |
| 179.17 | -3.25 | -3.25 |
| 420.35 | 2.70 | 2.70 |
| 347.40 | 0.44 | 0.44 |
| 780.95 | 2.22 | 2.22 |
| 424.99 | 0.39 | 0.39 |
| 225.29 | 1.52 | 1.52 |
| 303.36 | 0.92 | 0.92 |
| 263.38 | 2.63 | 2.63 |
| 314.41 | 1.46 | 1.46 |
| 361.35 | 1.13 | 1.13 |
| 367.92 | 2.85 | 2.85 |