Basic Information
ID: ALA995460
Type: Binding
Description: Displacement of [3H]3-chloro-4,7-difluoro-N-(4-methoxy-3-(pyridin-4-yl)benzyl)-N-(4-(methylamino)cyclohexyl)benzo[b]thiophene-2-carboxamide from human Smoothened receptor expressed in CHO-K1 cells by membrane filter binding assay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA995460
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.54 | 4.00 | 4.00 |
| 439.56 | 4.17 | 4.17 |
| 437.55 | 3.92 | 3.92 |
| 455.56 | 3.14 | 3.14 |
| 382.47 | 3.34 | 3.34 |
| 424.48 | 3.95 | 3.95 |
| 440.94 | 4.47 | 4.47 |
| 440.94 | 4.47 | 4.47 |
| 431.50 | 3.69 | 3.69 |
| 474.49 | 4.83 | 4.83 |
| 464.53 | 3.60 | 3.60 |
| 450.50 | 3.51 | 3.51 |
| 420.52 | 4.20 | 4.20 |
| 420.52 | 4.20 | 4.20 |
| 420.52 | 4.20 | 4.20 |
| 420.52 | 4.20 | 4.20 |
| 420.52 | 4.20 | 4.20 |
| 404.52 | 5.48 | 5.48 |
| 405.51 | 4.42 | 4.42 |
| 405.51 | 4.42 | 4.42 |
| 392.51 | 5.34 | 5.34 |
| 439.44 | 4.55 | 4.55 |
| 439.44 | 4.55 | 4.55 |
| 439.45 | 3.68 | 3.68 |
| 380.50 | 4.55 | 4.55 |
| 381.48 | 3.94 | 3.94 |
| 449.48 | 4.96 | 4.96 |
| 406.49 | 3.81 | 3.81 |
| 424.51 | 3.04 | 3.04 |
| 460.56 | 2.59 | 2.59 |
| 438.58 | 4.00 | 4.00 |
| 452.56 | 3.58 | 3.58 |
| 438.58 | 4.14 | 4.14 |
| 425.49 | 3.64 | 3.64 |
| 411.51 | 3.43 | 3.43 |