Assay Report Card

Basic Information

ID: ALA996989

Type: Binding

Description: Inhibition of NorA efflux pump in NorA knockout Staphylococcus aureus K1758 assessed as drug level required for two fold potentiation of berberine MIC at 1.56 to 100 ug/mL after 20 hrs by serial dilution method

Organism: Staphylococcus aureus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
193.253.833.83
238.253.743.74
273.313.083.08
272.332.482.48
218.263.713.71
251.283.623.62
237.263.533.53
251.283.623.62
223.283.333.33
251.283.623.62
223.283.333.33
251.283.623.62
223.283.333.33
296.283.533.53
268.273.243.24
296.283.533.53
268.273.243.24
296.283.533.53
268.273.243.24