Basic Information
ID: ALA996990
Type: Binding
Description: Inhibition of NorA efflux pump in wild type Staphylococcus aureus 8325-4 assessed as drug level required for two fold potentiation of berberine MIC at 1.56 to 100 ug/mL after 20 hrs by serial dilution method
Organism: Staphylococcus aureus
Activity Charts
Bioactivity
Activity Types for Assay ALA996990
MIC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 193.25 | 3.83 | 3.83 |
| 238.25 | 3.74 | 3.74 |
| 273.31 | 3.08 | 3.08 |
| 272.33 | 2.48 | 2.48 |
| 218.26 | 3.71 | 3.71 |
| 251.28 | 3.62 | 3.62 |
| 237.26 | 3.53 | 3.53 |
| 251.28 | 3.62 | 3.62 |
| 223.28 | 3.33 | 3.33 |
| 251.28 | 3.62 | 3.62 |
| 223.28 | 3.33 | 3.33 |
| 251.28 | 3.62 | 3.62 |
| 223.28 | 3.33 | 3.33 |
| 296.28 | 3.53 | 3.53 |
| 268.27 | 3.24 | 3.24 |
| 296.28 | 3.53 | 3.53 |
| 268.27 | 3.24 | 3.24 |
| 296.28 | 3.53 | 3.53 |
| 268.27 | 3.24 | 3.24 |