Basic Information
ID: ALA998549
Type: Functional
Description: Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of acetylcholine-induced intracellular Ca2+ mobilization by FLIPR assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA998549
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 546.62 | 3.40 | 3.40 |
| 546.62 | 3.40 | 3.40 |
| 560.65 | 3.79 | 3.79 |
| 560.65 | 3.79 | 3.79 |
| 574.68 | 4.03 | 4.03 |
| 572.66 | 3.79 | 3.79 |
| 540.62 | 2.75 | 2.75 |
| 554.65 | 3.14 | 3.14 |
| 568.68 | 3.53 | 3.53 |
| 568.68 | 3.53 | 3.53 |
| 580.69 | 3.53 | 3.53 |
| 602.70 | 4.64 | 4.64 |
| 616.72 | 4.32 | 4.32 |
| 582.71 | 3.87 | 3.87 |
| 596.69 | 2.86 | 2.86 |
| 546.62 | 3.40 | 3.40 |
| 560.65 | 3.70 | 3.70 |
| 560.65 | 3.70 | 3.70 |
| 560.65 | 3.70 | 3.70 |
| 574.63 | 3.42 | 3.42 |
| 555.64 | 3.56 | 3.56 |
| 565.07 | 4.35 | 4.35 |
| 598.62 | 4.71 | 4.71 |
| 530.63 | 3.69 | 3.69 |
| 468.55 | 2.51 | 2.51 |
| 494.59 | 2.90 | 2.90 |
| 532.60 | 3.01 | 3.01 |
| 776.67 | 5.53 | 5.53 |
| 779.47 | 4.62 | 4.62 |
| 718.56 | 4.00 | 4.00 |
| 704.65 | 4.61 | 4.61 |
| 716.62 | 4.32 | 4.32 |
| 688.56 | 3.54 | 3.54 |
| 769.46 | 5.17 | 5.17 |
| 735.02 | 4.51 | 4.51 |
| 716.57 | 3.57 | 3.57 |
| 735.02 | 4.51 | 4.51 |
| 762.71 | 5.31 | 5.31 |
| 712.59 | 4.11 | 4.11 |
| 760.63 | 3.88 | 3.88 |
| 714.60 | 4.17 | 4.17 |
| 678.61 | 4.36 | 4.36 |
| 730.60 | 3.87 | 3.87 |
| 715.59 | 3.44 | 3.44 |
| 725.58 | 3.73 | 3.73 |
| 690.55 | 3.98 | 3.98 |
| 742.66 | 4.88 | 4.88 |
| 704.58 | 4.37 | 4.37 |
| 804.68 | 5.09 | 5.09 |
| 712.59 | 4.11 | 4.11 |
| 722.65 | 4.38 | 4.38 |
| 715.63 | 3.89 | 3.89 |
| 768.57 | 4.88 | 4.88 |
| 735.02 | 4.51 | 4.51 |