Basic Information
ID: ALA998577
Type: Binding
Description: Inhibition of the ATP-mediated HIV1 reverse transcriptase D67N/K70R/T215F/K219Q mutant catalyzed 3'-azido, 3'-deoxythymidine excision from AZT-terminated DNA primers
Organism: Human immunodeficiency virus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA998577
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 351.01 | 1.54 | 1.54 |
| 318.24 | 2.13 | 2.13 |
| 346.30 | 2.91 | 2.91 |
| 367.28 | 0.94 | 0.94 |
| 282.12 | 0.23 | 0.23 |
| 351.28 | 2.86 | 2.86 |
| 277.15 | -0.49 | -0.49 |
| 365.30 | 3.25 | 3.25 |
| 343.21 | 2.40 | 2.40 |
| 343.21 | 2.40 | 2.40 |
| 304.22 | 1.74 | 1.74 |
| 332.19 | 1.38 | 1.38 |
| 297.14 | 0.23 | 0.23 |
| 392.67 | 2.55 | 2.55 |
| 374.22 | 2.02 | 2.02 |
| 394.20 | 2.18 | 2.18 |
| 312.15 | 0.24 | 0.24 |
| 357.24 | 2.71 | 2.71 |
| 325.19 | 0.30 | 0.30 |
| 379.19 | 2.68 | 2.68 |
| 376.21 | 2.04 | 2.04 |
| 376.21 | 2.04 | 2.04 |
| 357.24 | 2.33 | 2.33 |
| 379.19 | 2.68 | 2.68 |
| 297.14 | -0.19 | -0.19 |
| 346.01 | 1.50 | 1.50 |
| 357.24 | 2.45 | 2.45 |
| 388.25 | 1.91 | 1.91 |
| 379.19 | 2.68 | 2.68 |
| 392.67 | 2.55 | 2.55 |
| 357.24 | 2.45 | 2.45 |
| 311.17 | 0.88 | 0.88 |
| 394.20 | 2.18 | 2.18 |
| 388.25 | 1.91 | 1.91 |
| 284.12 | -1.02 | -1.02 |