Basic Information
ID: ALA998774
Type: Functional
Description: Antagonist activity at HA-tagged mouse AT1a angiotensin 2 receptor expressed in HEK293T cells assessed as decrease in angiotensin 2-induced intracellular calcium uptake
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA998774
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 212.25 | 3.04 | 3.04 |
| 257.25 | 2.95 | 2.95 |
| 238.29 | 3.44 | 3.44 |
| 422.92 | 4.27 | 4.27 |
| 210.28 | 3.50 | 3.50 |
| 240.30 | 3.66 | 3.66 |
| 230.24 | 3.18 | 3.18 |
| 230.24 | 3.18 | 3.18 |
| 230.24 | 3.18 | 3.18 |
| 246.69 | 3.70 | 3.70 |
| 246.69 | 3.70 | 3.70 |
| 246.69 | 3.70 | 3.70 |
| 291.14 | 3.81 | 3.81 |
| 291.14 | 3.81 | 3.81 |
| 338.14 | 3.65 | 3.65 |
| 257.25 | 2.95 | 2.95 |
| 257.25 | 2.95 | 2.95 |
| 269.30 | 3.00 | 3.00 |
| 269.30 | 3.00 | 3.00 |
| 269.30 | 3.00 | 3.00 |
| 226.28 | 3.35 | 3.35 |
| 226.28 | 3.35 | 3.35 |
| 226.28 | 3.35 | 3.35 |
| 242.27 | 3.05 | 3.05 |
| 242.27 | 3.05 | 3.05 |
| 242.27 | 3.05 | 3.05 |
| 240.30 | 3.61 | 3.61 |
| 240.30 | 3.61 | 3.61 |
| 254.33 | 4.17 | 4.17 |
| 272.30 | 3.06 | 3.06 |
| 240.30 | 3.66 | 3.66 |
| 240.30 | 3.66 | 3.66 |
| 256.30 | 3.36 | 3.36 |
| 256.30 | 3.36 | 3.36 |
| 256.30 | 3.36 | 3.36 |
| 260.72 | 4.01 | 4.01 |
| 260.72 | 4.01 | 4.01 |
| 260.72 | 4.01 | 4.01 |
| 271.27 | 3.26 | 3.26 |
| 271.27 | 3.26 | 3.26 |
| 271.27 | 3.26 | 3.26 |
| 305.36 | 2.00 | 2.00 |
| 242.27 | 3.06 | 3.06 |
| 242.27 | 3.06 | 3.06 |
| 258.27 | 2.76 | 2.76 |