Basic Information
ID: ALA999460
Type: Binding
Description: Inhibition of human DHFR assessed as rate of enzyme-dependent NADPH oxidation
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA999460
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 314.35 | 1.26 | 1.26 |
| 328.37 | 1.57 | 1.57 |
| 328.37 | 1.82 | 1.82 |
| 342.40 | 2.13 | 2.13 |
| 330.34 | 0.75 | 0.75 |
| 344.37 | 1.06 | 1.06 |
| 344.37 | 1.41 | 1.41 |
| 358.40 | 1.71 | 1.71 |
| 284.32 | 1.25 | 1.25 |
| 298.35 | 1.56 | 1.56 |
| 312.37 | 1.81 | 1.81 |
| 326.40 | 2.20 | 2.20 |
| 342.40 | 1.82 | 1.82 |
| 312.37 | 1.81 | 1.81 |
| 252.32 | 1.80 | 1.80 |