Basic Information
ID: ALA999754
Type: Binding
Description: Displacement of [125I]-(S)-2-((2S,4R)-4-(azetidin-1-yl)-1-(3-iodophenylsulfonyl)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)propanoic acid from VLA4 in human Jurkat cells washed with Hepes buffer by competitive binding assay
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA999754
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 660.36 | 4.91 | 4.91 |
| 674.39 | 5.30 | 5.30 |
| 675.38 | 3.85 | 3.85 |
| 715.44 | 4.60 | 4.60 |
| 715.44 | 4.60 | 4.60 |
| 729.47 | 4.99 | 4.99 |
| 743.50 | 5.38 | 5.38 |
| 729.47 | 5.03 | 5.03 |