ID: ALA148800

Max Phase: Preclinical

Molecular Formula: C10H16Cl2N3Pt+

Molecular Weight: 444.24

Molecule Type: Small molecule

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Properties

Molecular Weight: 444.24

Molecular Weight (Monoisotopic): 443.0364

AlogP:

#Rotatable Bonds:

Polar Surface Area:

Molecular Species:

HBA:

HBD:

#RO5 Violations:

HBA (Lipinski):

HBD (Lipinski):

#RO5 Violations (Lipinski):

CX Acidic pKa:

CX Basic pKa:

CX LogP:

CX LogD:

Aromatic Rings:

Heavy Atoms:

QED Weighted:

Np Likeness Score:

References

1. Najajreh Y, Perez JM, Navarro-Ranninger C, Gibson D..  (2002)  Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines.,  45  (24): [PMID:12431046] [10.1021/jm0201969]

Source

Source(1):

• Scientific Literature