ID: ALA2114475

Max Phase: Preclinical

Molecular Formula: C11H15NO2Se

Molecular Weight: 272.21

Molecule Type: Small molecule

Representations

Canonical SMILES:  Cc1ccc(C[Se]C[C@@H](N)C(=O)O)cc1

Standard InChI:  InChI=1S/C11H15NO2Se/c1-8-2-4-9(5-3-8)6-15-7-10(12)11(13)14/h2-5,10H,6-7,12H2,1H3,(H,13,14)/t10-/m1/s1

Standard InChI Key:  JKMVVSOYPSFMIC-SNVBAGLBSA-N

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Properties

Molecular Weight: 272.21

Molecular Weight (Monoisotopic): 273.0268

AlogP:

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HBA:

HBD:

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HBA (Lipinski):

HBD (Lipinski):

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CX Acidic pKa:

CX Basic pKa:

CX LogP:

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References

1. Andreadou I, Menge WM, Commandeur JN, Worthington EA, Vermeulen NP..  (1996)  Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of beta-elimination reactions in rat renal cytosol.,  39  (10): [PMID:8642562] [10.1021/jm950750x]

Source

Source(1):

• Scientific Literature