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trans-[Pt(OAc)2(NH3)(iquin)]

ID: ALA370881

Max Phase: Preclinical

Molecular Formula: C13H16N2O4Pt

Molecular Weight: 459.36

Molecule Type: Small molecule

Associated Items:

Bioactivity Summary Target Summary Assay Summary

Associated Targets(Human)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Natural Product: No	Oral: No	Chemical Probe: No	Parenteral: No
Molecule Type: Small molecule	Topical: No	First In Class: No	Black Box: No
Chirality: No	Availability: No	Prodrug: No

MESH ID	MESH Heading	EFO IDs	EFO Terms	Max Phase for Indication	References

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Molecular Weight: 459.36	Molecular Weight (Monoisotopic): 459.0758	AlogP:	#Rotatable Bonds:
Polar Surface Area:	Molecular Species:	HBA:	HBD:
#RO5 Violations:	HBA (Lipinski):	HBD (Lipinski):	#RO5 Violations (Lipinski):
CX Acidic pKa:	CX Basic pKa:	CX LogP:	CX LogD:
Aromatic Rings:	Heavy Atoms:	QED Weighted:	Np Likeness Score:

1. Ma ES, Bates WD, Edmunds A, Kelland LR, Fojo T, Farrell N.. (2005) Enhancement of aqueous solubility and stability employing a trans acetate axis in trans planar amine platinum compounds while maintaining the biological profile., 48 (18): [PMID:16134932] [10.1021/jm050539d]

Source(1):