| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ID: ALA3733064
Max Phase: Preclinical
Molecular Formula: C16H12O7
Molecular Weight: 316.27
Molecule Type: Small molecule
Associated Items:
Representations
Canonical SMILES: O=C1C=CC2C(=C1O)Oc1c(ccc(O)c1O)/C2=C\C=C(O)O
Standard InChI: InChI=1S/C16H12O7/c17-10-4-1-8-7(3-6-12(19)20)9-2-5-11(18)14(22)16(9)23-15(8)13(10)21/h1-6,8,18-22H/b7-3-
Standard InChI Key: CWBYMLFZPXXIAI-CLTKARDFSA-N
Associated Targets(Human)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1/gamma-2 71 Activities
Molecule Features
| Natural Product: No | Oral: No | Chemical Probe: No | Parenteral: No |
| Molecule Type: Small molecule | Topical: No | First In Class: No | Black Box: No |
| Chirality: No | Availability: No | Prodrug: No |
Drug Indications
| MESH ID | MESH Heading | EFO IDs | EFO Terms | Max Phase for Indication | References |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Properties
| Molecular Weight: 316.27 | Molecular Weight (Monoisotopic): 316.0583 | AlogP: 2.36 | #Rotatable Bonds: 1 |
| Polar Surface Area: 127.45 | Molecular Species: ACID | HBA: 7 | HBD: 5 |
| #RO5 Violations: 0 | HBA (Lipinski): 7 | HBD (Lipinski): 5 | #RO5 Violations (Lipinski): 0 |
| CX Acidic pKa: 1.68 | CX Basic pKa: | CX LogP: 1.60 | CX LogD: -4.18 |
| Aromatic Rings: 1 | Heavy Atoms: 23 | QED Weighted: 0.40 | Np Likeness Score: 1.50 |
References
| 1. (2010) Compositions and methods for inhibiting g protein signaling, |
Source
Source(1):