Document Report Card

ID: ALA1121393

Journal: J Med Chem

Title: Synthesis and biological activity of flavipucine analogues.

Authors: Girotra NN, Patchett AA, Zimmerman SB, Achimov DL, Wendler NL.

Abstract: A series of analogues of flavipucine was prepared possessing side chain as well as nuclear variants. The analogue with an octyl side chain (5d) was found to exhibit enhanced activity against several bacteria and fungi as compared with the natural product itself. The separation and characterization of the individual diastereoisomeric pairs both spectroscopically and with respect to chromatographic mobility have been effected.

CiteXplore: 7359536

DOI: 10.1021/jm00176a019