Ivermectin, a new broad-spectrum antiparasitic agent.

ID: ALA1121612

Journal: J Med Chem

Title: Ivermectin, a new broad-spectrum antiparasitic agent.

Authors: Chabala JC, Mrozik H, Tolman RL, Eskola P, Lusi A, Peterson LH, Woods MF, Fisher MH, Campbell WC, Egerton JR, Ostlind DA.

Abstract: 22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.

CiteXplore: 6893469

DOI: 10.1021/jm00184a014

Patent ID: ┄