Document Report Card

ID: ALA1123801

Journal: J Med Chem

Title: Synthesis and antifungal activity of new 1-vinylimidazoles.

Authors: Ogata M, Matsumoto H, Shimizu S, Kida S, Shiro M, Tawara K.

Abstract: Carbonyl compounds I were subjected to an imidazole transfer reaction with N,N'-sulfinyldiimidazole or N,N'-carbonyldiimidazole to obtain the diimidazole II and the monoimidazole III. Various 1-vinylimidazoles IV, derived from o-hydroxyacetophenones by imidazole transfer reaction, were alkylated to furnish the title compounds V. The structure-activity relationships of these 1-vinylimidazole compounds V are described.

CiteXplore: 3302257

DOI: 10.1021/jm00391a014